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Index > Protein center > Sirt2(Gene name) > Mouse
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  • Sirt2 (Gene name),
  • NAD-dependent deacetylase sirtuin-2 (Protein name ),  SIRT2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Sirt2(Sir2l2);
    Protein name:
    NAD-dependent deacetylase sirtuin-2;
    Alternative:
    SIR2-like protein 2(mSIR2L2);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with HDAC6, suggesting that these proteins belong to a large complex that deacetylate the cytoskeleton.
    Function:
    NAD-dependent deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
    Subcellular Location:
    Cytoplasm cytoskeleton Colocalizes with microtubules.
    Protein Attributes:
    Sequence length:
    389
    Sequence:
    50:
    MAEPDPSDPL | ETQAGKVQEA | QDSDSDTEGG | ATGGEAEMDF | LRNLFTQTLG | 
    100:
    LGSQKERLLD | ELTLEGVTRY | MQSERCRKVI | CLVGAGISTS | AGIPDFRSPS | 
    150:
    TGLYANLEKY | HLPYPEAIFE | ISYFKKHPEP | FFALAKELYP | GQFKPTICHY | 
    200:
    FIRLLKEKGL | LLRCYTQNID | TLERVAGLEP | QDLVEAHGTF | YTSHCVNTSC | 
    250:
    RKEYTMGWMK | EKIFSEATPR | CEQCQSVVKP | DIVFFGENLP | SRFFSCMQSD | 
    300:
    FSKVDLLIIM | GTSLQVQPFA | SLISKAPLAT | PRLLINKEKT | GQTDPFLGMM | 
    350:
    MGLGGGMDFD | SKKAYRDVAW | LGDCDQGCLA | LADLLGWKKE | LEDLVRREHA | 
    389:
    NIDAQSGSQA | PNPSTTISPG | KSPPPAKEAA | RTKEKEEQQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    E0430r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    E0430m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    E0430m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    E0430h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    E0430r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    E0430h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    U0430m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    U0430r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    U0430h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    U0430m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    U0430r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    U0430h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    P0430Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    P0430Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    P0430Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    P0430Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    P0430Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Cat.:
    P0430Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Monoclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Monoclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Monoclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Monoclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Monoclonal Antibody for Mouse NAD-dependent deacetylase sirtuin-2
    Protein for Mouse NAD-dependent deacetylase sirtuin-2
    Protein for Mouse NAD-dependent deacetylase sirtuin-2
    Protein for Mouse NAD-dependent deacetylase sirtuin-2
    Protein for Mouse NAD-dependent deacetylase sirtuin-2
    Protein for Mouse NAD-dependent deacetylase sirtuin-2
    Protein for Mouse NAD-dependent deacetylase sirtuin-2

    R&D Technical Data

    s

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤7.8%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤10.9%

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    Recovery

    Recovery was determined by spiking various levels of SIRT2 into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    95-103

    Plasma

    98

    96-101

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of SIRT2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    91-107%

    93-104%

    92-104%

    95-103%

    EDTA plasma(n=5)

    92-105%

    94-105%

    93-105%

    93-106%

    heparin plasma(n=5)

    95-102%

     

    96-102%

    94-102%

    96-101%

     

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